A BRIEF HISTORY OF SBRT:
“Intracranial Stereotactic Radiosurgery (SRS) was a new treatment method for brain tumors introduced in the twentieth century to deliver tight spatial/temporal distribution using a high precision technique. The clinical experience from intracranial SRS, together with the technical developments in conventional RT, initiated the development of Stereotactic Body Radiation Therapy (SBRT) for extracranial tumors characterized by a very high dose per fraction, delivered in a short time. This was started at the Swedish Karolinska University hospital in 1991 with tumors in the liver and lungs by Bromgren and Lax [1–3]. In parallel this method was developed in Japan and clinically introduced in 1994 for lung tumors [4–6]. During the last 5 years of the nineties, SBRT was introduced in several centers in Europe, Japan and USA. Wulf and Herfarth in Germany reported theis clinical results on lung cancer in 2001, followed by Timmerman in USA in 2003. “
STAGES IN THE DEVELOPMENT OF SBRT:
“SBRT is characterized by patient immobilization, limiting normal tissue exposure to high-dose radiation, preventing or accounting for organ motion (e.g., respiratory motion), the use of stereotaxy, and the subcentimeter3,4 accuracy of the delivered dose. The key components of a SBRT procedure are target delineation,5 treatment planning, and treatment delivery.”
PIONEERS IN THE DEVELOPMENT OF SBRT:
“The development of stereotactic body radiation therapy (SBRT) began in the early 1990s at the Karolinska Institute (Stockholm, Sweden) with researchers Ingmar Lax and Henric Blomgren and was derived from the techniques and procedures of stereotactic radiosurgery (SRS). “
“During the last 5 years of the nineties, SBRT was introduced in several centers in Europe, Japan and USA. Wulf and Herfarth in Germany reported theis clinical results on lung cancer in 2001, followed by Timmerman in USA in 2003.”
REFERENCES:
https://link.springer.com/chapter/10.1007/978-4-431-54883-6_1
https://www.ncbi.nlm.nih.gov/books/NBK55717/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316669/